Mr. Pauls has served as Savara’s Chief Executive Officer since December 2020, Chair of the Board of Directors since September 2020, and the company’s Interim Chief Executive Officer from September 2020 to December 2020. He has been a member of Savara’s Board of Directors since April 2017 and was Chair of the Mast Therapeutics (NYSE: MAST) Board of Directors. (Savara closed a reverse merger with Mast Therapeutics in April 2017.) Previously, Mr. Pauls was the Founder of Spartan Biopharma Insights, LLC, where he provided strategic advice to institutional investors and company management teams on investment thesis assessment, capitalization strategy, mergers and acquisitions, clinical execution, and commercialization. He also previously served on the Zyla Life Sciences Board of Directors, which merged with Assertio Therapeutics in 2020. Prior to that, Mr. Pauls was President and Chief Executive Officer and, from October 2015 to November 2019, a member of the Strongbridge Biopharma plc Board of Directors. Strongbridge was a publicly traded, rare disease focused biopharmaceutical company that he took public via IPO on the NASDAQ. The company merged with Xeris Biopharma in 2021. Prior to Strongbridge, Mr. Pauls was Chief Commercial Officer of Insmed, Inc., a publicly traded global biopharmaceutical company focused on rare respiratory diseases. Prior to Insmed, he worked at Shire Pharmaceuticals most recently as Senior Vice President, Head of Global Commercial Operations. Earlier in his career, Mr. Pauls held senior U.S. and global commercial leadership positions at Bristol-Myers Squibb and Johnson & Johnson. Mr. Pauls holds B.S. and M.B.A. degrees from Central Michigan University and a J.D. from Michigan State University College of Law.
Mr. Lowrance has served as Savara’s Chief Financial Officer since November 2016. From September 2014 to October 2016, Mr. Lowrance served as the Chief Financial Officer and Treasurer of Edgemont Pharmaceuticals, a fully-integrated specialty pharmaceutical company with multiple marketed products in the CNS space. From April 2011 to September 2014, Mr. Lowrance served as the Chief Financial Officer and Secretary of Acucela Inc., a clinical-stage biotechnology company that specializes in ophthalmic therapeutics, where he was responsible for overseeing all aspects of Acucela’s day-to-day operations, business development and growth endeavors, investor relations and corporate communications. While at Acucela, Mr. Lowrance helped lead a $162 million international IPO, with a listing on the Tokyo Stock Exchange. From March 2003 to April 2011, Mr. Lowrance was Vice President and Chief Financial Officer of Cumberland Pharmaceuticals Inc., a specialty pharmaceutical company focused on commercializing branded prescription products, where he oversaw all aspects of finance and accounting, business and growth strategy and product development. Mr. Lowrance, a CPA, holds a B.B.A. in Accounting from the University of Georgia.
Dr. Chowdhury joined Savara as Chief Medical Officer in November 2019. Previously he was at AstraZeneca where he held the position of Senior Vice President, Chief Physician-Scientist for Respiratory Inflammation and Autoimmunity Late Stage Development in Biopharmaceuticals. For 16 years prior to that, Dr. Chowdhury served as Director, Division of Pulmonary, Allergy, and Rheumatology Products, Center for Drug Evaluation and Research (CDER) at the U.S. Food and Drug Administration (FDA) where he provided scientific and regulatory oversight of both common and rare diseases such as asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, cystic fibrosis, rheumatoid arthritis, systemic lupus erythromatosis, and various autoimmune and inflammatory diseases. Dr. Chowdhury is a medical doctor, and also holds a Ph.D. in Immunology. He completed Internal Medicine Residency training from the Wayne State University School of Medicine, Detroit, Michigan, and Fellowship training in Allergy and Immunology from the National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, Maryland. He is double board certified in Internal Medicine and Allergy and Immunology.
Dr. Clarke joined Savara as Executive Vice President, Global Technical Operations in September 2021. With more than four decades of experience in the Biopharma sector, he has extensive knowledge of late-stage development, manufacturing, supply chain and licensing in the U.S. and Europe. To date, Dr Clarke has been part of licensing and launch teams for eight biological products in several different therapeutic areas. Prior to joining Savara, Dr. Clarke held positions of increasing responsibility with companies in Europe and the US, including multi-national corporations and BioPharma start-ups. He has held senior leadership roles at numerous companies, including Insmed, Savient Pharma, and Bayer Biologicals. Dr. Clarke holds a Ph.D. in Microbial Physiology from Imperial College, London.
Dr. Desai serves as Savara’s Head of Clinical Development. Prior to joining Savara, she was leading early- and late-stage clinical development programs across multiple therapeutic areas at AstraZeneca. During her 15-year tenure at AstraZeneca, Dr. Desai worked with both large and small molecule therapeutics and with multiple collaborators and partners. She has led a diverse portfolio of products to successful global submissions and approvals, including advisory committee experience. In addition to her development experience, Dr. Desai brings cross-cultural leadership skills, having successfully built an enterprise capability in Warsaw, Poland which handled medical and safety monitoring for late-stage Phase 3 programs. Dr. Desai is a board-certified Internal Medicine physician. She earned her M.D. from Jefferson Medical College in Philadelphia, completed a Residency in Internal Medicine with Rush-Presbyterian St. Luke’s Hospital in Chicago, followed by a Fellowship in Clinical Pharmacology with the University of California San Francisco.
As Savara’s Chief of Staff, Ms. Erickson has line management responsibilities, an enterprise-wide focus on operational excellence, and leads the company’s global investor relations, corporate affairs, and advocacy efforts. She is a seasoned executive with many years of experience within the biotech and pharmaceutical sectors. Ms. Erickson has held leadership roles of increasing responsibility within corporate, consulting, and agency settings at companies like Mirati Therapeutics, Pfizer, and Ogilvy.
Mr. LaPree joined Savara as Senior Vice President, Global Regulatory Affairs and Quality Assurance in August 2021. He has more than three decades of domestic and international drug development experience encompassing all aspects of global Regulatory Affairs and Quality Assurance. Prior to joining Savara, Mr. LaPree was SVP, Head of Global Regulatory Affairs and Quality Assurance at Annexon Biosciences. Prior to that he was VP, Head of Global Regulatory Affairs and Medical Writing at Astex Pharmaceuticals and previously served as SVP, Head of Global Regulatory Affairs at Jazz Pharmaceuticals. Mr. LaPree has held leadership roles of increasing responsibility at several other companies, including Shire Pharmaceuticals, Bristol-Myers Squibb Company, and Johnson & Johnson. Mr. LaPree holds a B.S. in Chemistry from Rochester Institute of Technology and a M.S. in Environmental Sciences from the University of Rochester School of Medicine and Dentistry.
Ms. McCabe serves as Savara’s SVP of Legal Affairs. Prior to joining Savara, Ms. McCabe practiced corporate and securities law at Wilson Sonsini Goodrich & Rosati, Professional Corporation, where she represented life sciences and technology companies in a variety of matters, including entity formation and structuring, venture capital financings, corporate governance, mergers and acquisitions, public offerings, public company disclosure requirements, and SEC compliance matters. Ms. McCabe holds a B.S. in Accounting from Canisius College and a J.D. from the University of Texas School of Law.